Understanding bioorganic structure and reactivity for the precise control of molecular properties and transformations

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At the intersection of chemistry and biology, we study:

Bioorthogonal 1,3-Dipolar Cycloadditions

Cycloaddition reactions have consumed the field of bioorthogonal chemistry...

Stereoelectronics of Enzyme Catalysis

Molecules adopt geometries to facilitate effective delocalization—the basis of stereoelectronic effects...